The airline said it will begin flying this fall from Washington National Airport to San Juan, Puerto Rico with connecting service to St. Thomas.
A start date is uncertain. An effort to book such a flight, on the JetBlue Web site, was unsuccessful.
"Award-winning Jet Blue intends to offer one daily nonstop round trip flight to San Juan's Luiz Munoz Marin International Airport, with connecting service to St. Thomas," the airline said in a news release. "JetBlue has long had a simple formula for deciding which markets to serve: we look for routes that are underserved, overpriced, or both."
JetBlue says it is Puerto Rico's largest airline, offering service nonstop to 11 destinations on the US mainland and in the Caribbean.